Thanks for your reply Dave, I had initially hoped for the route that you have suggested but was unsure if the Tioga pass would be open by the time of my trip.

If I was to take this route, how long would the drive be to Yosemite from Vegas and could you recommend any camp sites?

Is there a good alternative route to head for Yosemite from Vegas if Tioga pass is still closed by the time of my journey (mid June)?