From the Interstates, this is a fairly straightforward drive. It's an industrial corridor between Buffalo and Akron; farmland for most of Ohio, interspersed with the occasional urban area; and rolling hills and forests through Kentucky. Since you're going to give yourself a little extra time, however, you might like to take NY-5 along Lake Ontario around Dunkirk, stop and see Cuyahoga Valley National Park south of Cleveland, follow the Ohio River on US-42 between Cincinnati and Louisville, or visit Mammoth Cave National Park just before reaching Bowling Green.

AZBuck