Danny,

Roadtripping in winter can be really great -- less crowds, different weather, etc. But some of those driving days seem to be assuming that you will be able to drive 70 mph+. If you hit winter storms, your average speed may approach 30 mph and may require stopping and waiting for roads to re-open. That can be fun too, so just be prepared.

Almost any place in USA is different than LA. What kinds of things are you seeking?