The reality is over the course of a 2000 mile trip, the things you could see and do are in the millions. There's just no way we can realitistically narrow down all of the possibilities until you've got a better idea of what it is you are after.
That means you need to take the first step. There are lots of resources on this site, including the map center and many other articles, that can help you narrow in on some ideas.
Once you have a better idea of your trip, then we can help you put everything together.