Hi there,

I have the following as a wish list. Is this a possibility or not?

San Francisco or Phoenix to enter USA and leave by vegas.

I'd like to see Bryce, zion, GC, monument valley, yosemite i guess.
Yes, it is.

The thing is, am i better off with a circular route or a one way? Is car hire much more expensive one way?
They really are just choices, you can see as many different places in a loop as you can a single route, it would mainly depend on if there is something you must see outside of that loop or you want a different destination.
You would have to look at the different one way drop of fees each company charges, at a guess $2-$300.

If i do a circle, which of the above should i miss out?
They are still all possible, as shown in our 15 days. The thing is we are all individuals and a long drive to some maybe a walk in the park for others so we need to establish how many miles/hours you want to devote to travelling and how many to staying in one place, this will determine how much you can get to see, or at least the possibilities.

An example could be
2 nights San Fran > 2nights Yosemite > 2 nights Death valley/Vegas > 2 night Zion >
1 night Bryce > 1 night Monument valley > 2 nights Grand canyon.

Please remember it's just an example, but that is a fairly relaxed pace with 12 nights gone and 3 remaining. Now if you was flying out of Vegas you could skip it on the way down and end up there, maybe spending more time between Bryce and M/V such as lake powell/Page or towards Phoenix such as the Sedona area.
If you headed back to San Fran you could see the Giant sequoias through part of the park or part of the coast would be an option[but poss a bit rushed
Like I say just ideas so you can piece bits together, but it's when you have these bits in place is when we can really help piece it together with overnight stops, timing et.c.

Have you tried a mapping tool yet such as Google maps. Click on the link and you will find the "get directions"
tool on the left of the page, type in a start and finish location and it will give you the mileage and travel time for each possible stop. The mileage is fine but the time does'nt allow for any delays, lunch, fuel stops or sightseeing so you have to allow plenty of time for that.