Like Michael mentioned above, I-75 might be a better route. Dave Hunter's "Along I-75" has been freshened up for this new year. I haven't published my review of the 2007 version yet, but my review of the 2006 is online here.
A couple of nice "time-outs" that your kids might enjoy -- Snook's Dream Cars at exit 179 (in Ohio) has some historic cars and a restored 1930's general store. The pizza place on the old town square at Troy, Ohio is fun and one of my all-time stores is the Tippecanoe Trading Post in Tipp City (exit 68). Better than Disneyworld -- everything in this store (based on stuff used in the 1700's) is for sale.
In Kentucky, another best bet for road grub can be found at exit 159 at the Country Grill. In Chattanooga, you might enjoy the Tennessee Aquarium and the entire route goes through and around lots of Civil War sites.
Mark