I know several who have done this trip and had a fantastic time, however they have done it in the summer months. I would check the various weather sites. www.wunderground.com is a good one. It has historical data so you could check last year during your proposed travel dates to see what the weather was like and get a good idea of what to expect.

For example, the temp in Haines Junction, Yukon Terroritory, was 12 deg. F last year on Nov. 10th. Yikes! I have a feeling it will be pretty treacherous driving that time of year.