From San Francisco to LA, I would take the breathtaking Pacific Coast Highway. It is a destination in itself. Rather than seeing Disneyland, consider Florida's gigantic Disney World (if Florida is your final destination). It would be a nice way to unwind after weeks of travel and you might be able to fly from Orlando.

I live in Michigan and cannot imagine why you would want to visit Detroit! There are miles of burnt down homes as you enter the city. I've lived in the Suburbs for over 60 years and seldom head downtown except for the casinos or theaters. On the other hand, Michigan does have some wonderful attractions and parks. Mackinaw Island is a fantastic vacation destination if you don't mind walking, riding bikes or horses because vehicles are banned there! For more natural beauty, head to the Upper Peninsula.