Unless you are used to working a graveyard shift, I'd strongly recommend driving during daylight hours. Being solo, it will be way way way too easy for you to drift off behind the wheel especially if you are trying to do this during hours where your body thinks you should be sleeping.

You didn't say exactly where in AL you are starting from, but unless you are starting from say Huntsville or somewhere else in the northern edge of the state, even trying to make Boston in just two days really pushes beyond what we'd recommend, especially for a solo traveler. It should also be noted that going to DC is also likely going to be far too far to try to get to in just one day.