Have to disagree with that I-10 Stretch
That's is one of my favorite stretches of road, although I always get off of I-10 and take I-20. There is the best rock station out there (I always have to hunt for it). I feel like I'm driving on Mars or some other exotic barren wasteland, listening to rock classics and going 75 mph. Nothing better.
NOLA - have you booked a hotel room yet? There are still very few hotel rooms available in the state of Louisiana even now. I know my parents had a tough time finding a room for Lake Charles and New Orleans (Metarie, Kenner, etc) will probably be as tough. The evacuees were just forced to leave hotel rooms within the last month and there are still many contractors and businesses renting the rooms.
Laura
Not sure if it's open, but
Preservation Hall is a must. Also, just walk down Bourbon Street and keep your ears open. Most of the bars used to keep their doors open and you could hear all sorts of jazz coming out of the clubs.
Laura