Any suggestions for a pretty route between these two cities? I am thinking of making a detour to Perryville, KY for tea at the Elmwood Inn. Went up the East side of the Mississippi the last time and am open to going up the West side this time. Don't have to stick to the Interstates. I prefer to meander, mosey, and sashay. Any good antiquing towns? Any interesting place a half day's drive from St. Louis to stop the night before in order to be in SL around noon the next day? Am returning from SL to Tampa, FL so any suggestions for the return will be appreciated as well.