Originally Posted by Southwest Dave
You could easily spend 2 or 3 days exploring Big Bend, Rio Grande village Boquillas canyon, Chisos basin and the Ross Maxwell scenic drive down to Santa Elena canyon are some of the highlights. You could exit Big bend via Lajitas to Presido in FM170 which follows the Rio Grande and Mexican border with various viewpoints and an old movie location. Heading north towards Marfa you will pass Shafter ghost town and Elephant rock. From Marfa you could take US90 to Van horn of continue to Fort davis historic park and TX118 through Davis mountains and Madera canyon to I-10. You would need to carefully check lodgings at Big bend and depending on when you are visiting, the weather.