I meant I'd forgo the Interstates altogether. The all-Interstate route from Savannah to Panama City would take you south to JAX on I-95 thence west on I-10, passing through considerable urban/suburban congestion at JAX and probably again to the west. The brief glance I took at a map showed highways through Waycross, Jesup, and Valdosta. The south Georgia Coastal Plain and its small towns would be a more enjoyable drive for most of us provided that time was not of the essence. In September one is likely to encounter school buses on the rural highways in the morning and mid afternoon, and logging trucks and farm equipment can be counted upon to slow you down at some point.