We are moving and have decided to ship one car and take the minivan for a road trip. When we moved out to VA from Northern CA, we took 80-->Denver-->St Louis-->West Virginia-->Northern VA and it was mid April. It was great and we did it without kids in a week at a semi leisurely pace. Now, two kids later and a few months earlier in the year, we are looking for suggestions on an alternate route. Knowing that weather is unpredictable, and so are kids, we will build in extra days, but as far as a route to take, we are pretty much starting from scratch.
We are still in the beginning phases of planning so are open to all suggestions... especially from anyone with experience traveling with a 1 and 3 year old! :) Actually, this summer we spent about 7 days traveling from VA up through most of NY, mix of camping and hotels. It was great, but really didn't spend more than 4-5 hours in the car each day. I am not sure we would be able to adhere to that kind of a timeline for a trip cross country.