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You are going to have to go over some high passes to go west from where you are, no matter what you do.
US-24 has a couple between Colorado Springs and Salida. Going west from Alamosa, Wolf Creek Pass on US-160 is a rough one. If weather does look to be an issue, the safest thing for you to do at this point is take I-25 to Albuquerque and then I-40 to go west. At least the Interstates are safer than the winding 2 lanes.
Plannnow is to head to Salida, roads seem to be clear, then head south to Alamosa and then, maybe to Taos. Are the sand dunes worth taking a detour? I might then visit a place I worked briefly about 30 years ago, Los Alamos. Eventually, may go west or find Route 66 backbtobSt. Louis.