I guess the weather at the time of traveling will diticate my route as we go.
Yes, that is your best bet. As you get closer to your departure date, start watching the US national weather reports. Make your decision about routing just before you leave. Carry paper maps and/or a US road atlas, in case the weather-guessers are wrong and you need to divert. Have an extra day or two where you can pull over and wait one out, as well. The interstates are the last to close and the first to get serviced during a weather issue, because they are so important to the economy (i.e. "the goods must get through").

Keep us posted on how you ended up going and about your trip, either by adding to this thread, or by starting one in the Road Trip Field Report forum.